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Rep 78 , 173193 (2026)

Tian C, Reyes I, Johnson A, Masurkar AV (2025) Impact of dendritic spine loss on excitability of hippocampal CA1 pyramidal neurons: a computational study of early Alzheimer disease

To address these challenges, researchers are exploring various innovative strategies

For example, on one hand, the addition of ICIs counteracts PD-L1 upregulation induced by cGAS-STING pathway activation, thereby maximizing T cell activation