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In the face of restricted glucose availability, immune cells exhibit a profound dependence on the uptake and catabolism of glutamine as a means to sustain the TCA cycle, a pivotal process crucial for their ongoing viability and functionality [114,115,116]

After assessing the literature, we divided medications into one of three groups: medications that should be avoided in individuals with G6PD deficiency, medications that were considered unsafe by at least one source, but according to our review can probably be given safely in normal therapeutic dosages to individuals with G6PD deficiency as evidence does not contravene their use, and medications where no evidence at all was found to contravene their use in G6PD-deficient patients

An ongoing clinical trial will compare 2-year overall survival and outcomes related to SCD in patients that undergo transplant compared with current standard of care (ClinicalTrail.gov Identifier: NCT02766465)

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