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SKU: 36636550435
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Description

Leonard, W., Zhang, P., Ying, D., & Fang, Z

doi: 10.1186/s12870-022-03455-6 16 ChenCNaveedHChenK

Macroautophagy/autophagy promotes resistance to KRAS(G12D)-targeted therapy through glutathione synthesis

By monitoring for the appearance of the ~9 kDa C3a fragment, no cleavage products could be detected, suggesting that Chi homologs did not exert C3b/C3 cleavage activity under the tested conditions

In addition, we found a strong relationship between endoplasmic reticulum (ER) stress and ferroptosis, and we therefore speculated that sustained ER stress might be a prerequisite for ferroptosis in JEV and HSV-induced diseases