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[DOI] [PubMed] [Google Scholar] AlSeadi, H

24 ,

Blocking Dectin-1 prevents colorectal tumorigenesis by suppressing prostaglandin E2 production in myeloid-derived suppressor cells and enhancing IL-22 binding protein expression

However, researchers emphasize that careful consideration of causality relationships and genetic factors remains essential for proper scientific interpretation

GI cancers arise from complex mechanisms involving chronic inflammation, genetic mutations, and disrupted signaling pathways that promote uncontrolled cell growth and metastasis