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Currently, the only available treatment for the condition is a strict, life-long gluten-free diet that, despite being safe and often effective, is associated with several challenges

This text does not replace a veterinary consultation and does not contain any therapeutic claims.

Meanwhile, hypoxia can also induce XBP1 expression and activate its mRNA splicing in a HIF-1 dependent pathway, leading to increased XBP1s (77)

It is important to mention that various studies have shown that in animal models with bleomycin-induced lung injury, vitamin B3 (niacin or nicotinamide) is highly effective in preventing lung tissue damage [7]

Hence, MYC activation elicits numerous hallmarks required for autonomous tumor growth