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While the experimental models employed in PD have shown connections to human health, it remains a daunting task to translate mechanisms of action observed in in vitro and in vivo studies of natural compounds to clinical outcomes in human trials, where it is a critical step in drug development

Moreover, although the decrease in NAD(P)H induced by FCCP was initially alike in both islet types, it rapidly became slower in the N5-Tr islets, so that, after 10 min of FCCP treatment, NAD(P)H autofluorescence remained significantly higher than in 0.5 mmol/l glucose in N5-Tr but not N5-WT islets

[DOI] [PubMed] [Google Scholar] 194.Ji P., Yu T., Liu Y., Jiang J., Xu J., Zhao Y., Hao Y., Qiu Y., Zhao W., Wu C

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