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Classical FD (HHC type 4A) is due to loss of function mutations in SLC40A1 that impair iron export

Nucleic Acids Res 39 , e142 (2011)

Results: Study 1: Patient background observation period (median): 5.2 years, age(median): 52 (45-58), male were 8242 cases (71%), 2556 patients (22%) were taking NA, and the average ALT during the observation period (median) was 23 (20-29) U/L