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J Contemp Dent Pract

Neither the short follow-up period of 1 month nor the long period of 12 months showed any significant adverse reactions

84 , 173 Studies have shown that the combination of chemotherapeutic drugs (such as ADM and DDP) and the antimicrobial peptide -defensin can improve the sensitivity of multidrug-resistant breast cancer MDA-MB-231 cells to the chemotherapeutic drugs and effectively enhance the cytotoxic effect of such chemotherapeutic drugs