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This may lead to the discovery of new therapies for sepsis and septic renal injury, as well as other disorders that lead to glycocalyx degradation (Figure 3)

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J Biol Chem 271:2431324316 Lee M, Schwab C, Yu S, McGeer E, McGeer PL (2009) Astrocytes produce the antiinflammatory and neuroprotective agent, hydrogen sulfide

One possible mechanism is that ROS accumulation due to aberrant oxidative stress in erythroid cells affects erythropoiesis by inducing oxidative denaturation of the band 3 protein