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doi: 10.1158/2326-6066.Cir-17-0716 96 WanCSunYTianYLuLDaiXMengJet al

The expression level of HO-1 is notably reduced in the EAOC group in comparison to the benign OE group, as indicated by the diminished presence of 8-hydroxy deoxyguanosine (8-OHdG) in the fluid

Cysteine is known to stimulate glutathione synthesis[23], and cysteine availability is often the limiting factor for intracellular glutathione synthesis[24]