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Although most studies have focused on AIM2 sensing of nuclear or pathogen-derived DNA, recent work suggests that mtDNA released during apoptosis or mitochondrial damage can also activate the AIM2 inflammasome, amplifying inflammation [42]

Lifestyle Recommendations for Muscle Growth and IGF-1 LR3 Pathway Support Consistent lifestyle habits are the most durable and evidence-supported way to reinforce the biological pathways associated with IGF-1 LR3 and muscle growth and recovery