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When in doubt, use compounds sequentially rather than simultaneously, rotating through different mechanisms during consecutive cycles

In this context, it is possible that the activation of GSH synthesis helps to cope with the oxidative conditions caused by RBOHs following ER stress

[Google Scholar] 76.Yim W, Takemura K, Zhou J, Zhou J, Jin Z, Borum RM, Xu M, Cheng Y, He T and Penny W, ACS Nano, 2021, 16, 683693

The metabolic demands of infiltrating B cells within this intrarenal nichecharacterized by hypoxia and nutrient limitationare likely met by the same glycolytic reprogramming observed in secondary lymphoid organs, enabling local autoantibody production and contributing directly to tissue injury (125, 126)

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