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Harshbarger argued in the letter that the FDA has been too strict, which has led peptide users to sketchier sources: Yet FDA policy significantly restricts compounding of these peptides even where no FDA approved alternative exists leaving patients without safe, regulated access

People might experience some minor issues such as injection site sensitivity

Susan Spratt, an endocrinologist and the senior medical director of the Population Health Management Office at Duke Health in North Carolina, who was not involved in the studies, applauded the research, saying the findings show that obesity is not a vanity issue. This is about treating a major health problem that reduces significant morbidity and mortality, she said

If cloudiness persists, let the vial rest at room temperature for 5 minutes and swirl again

Doses often cited range from 200 to 500 mcg (micrograms) administered daily, although some go up to 1000 mcg