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Vitamin B12 injections are also gaining in popularity and availability

(2009) Vitamin B12 may be more effective than nortriptyline in improving painful diabetic neuropathy

Small fibers are preferentially impaired in PDPN

Nielsen SCA, Yang F, Jackson KJL, Hoh RA, Rltgen K, Jean GH, et al

Use with caution if you have kidney or liver conditions, and consult a healthcare professional if pregnant, breastfeeding, or taking other medications