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In addition to megaloblastic anaemia, the other classic pathophysiological manifestation of B12 deficiency is neuronal demyelination, which affects both the peripheral and central nervous systems [293] and shown in Figs 9 and 10

The bacterial changes thus resulting could weaken the gut barrier and facilitate the translocation of harmful bacteria from the gut to the blood

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Ineichen BV, Keskitalo S, Farkas M, Bain N, Kallweit U, Weller M, Klotz L, Linnebank M