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These T-LNPs significantly improved BBB penetration and enhanced the neuroprotective effects of Fer-1 in a murine stroke model, as evidenced by increased fluorescence distribution in brain tissues at 6 h postadministration and reduced cerebral infarction

We highlight the common mechanisms of ALAs renal protective actions that include decreasing oxidative damage, increasing antioxidant capacities, counteracting inflammation, mitigating renal fibrosis, and attenuating nephron cell death

PMID 25701330

f , g , Quantification of PS exposure in dHL-60 WT, KO, and XKR8 mutant cells (KO + XKR8 2DA , KO + XKR8 S/T-3A ) treated with doxorubicin (10 M) ( f ) or PMA (100 nM) ( g ) ( n = 3)

LWT, 145 (111322), 19