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Asymmetric dimethyl arginine, which inhibits endothelial NO and promotes ROS production in endothelial cells [29], serves as a major independent risk factor in ESRD [30]

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Eur J Biochem 1999

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This mechanism explains accelerated healing across multiple tissue types including bone

Concerning the surgical procedure that was carried out for patients in the two studied groups, the aortic clamp duration and the cardiopulmonary bypass time were more or less comparable in both groups