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Ferritin-targeted strategies remain largely underexplored in brain cancers and could represent a novel approach to induce ferroptosis in embryonic-origin tumors, such as glioblastoma (GBM) and medulloblastoma (MB), potentially sensitizing CSCs to conventional therapies by reducing their antioxidant capacity

Next, we analyzed the conserved sequences of XIST promoters from human genomes in the JASPAR database, and two conserved sequences were identified within the 2000 bp upstream from the transcription start site

An experimental investigation found that -carotenoids protect against skin photo-related illnesses by scavenging excited triplet forms of endogenous photosensitizers in patient blood and skin, including protoporphyrin, a hereditary erythropoietic protoporphyria [153]

doi:10.3389/fphys.2019.01531

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