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In this case, you'd add 3.0 mL of bac water

10.1016/j.cell.2011.02.018 [DOI] [PMC free article] [PubMed] [Google Scholar] 78.Shima T, Matsui T, Jesmin S, Okamoto M, Soya M, Inoue K, et al

That might not sound catastrophic, but when you are on a carefully calibrated dosing protocol , a 10 percent reduction means your 0.5 mg dose is really delivering 0.45 mg