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roughly 50-98 % of an administered dose is renally excreted unmetabolized, underscoring the low intrinsic toxicity

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to 100 ml These water-soluble B vitamins play vital roles in energy metabolism, red blood cell formation, skin and nerve health, and stress response

Monthly vitamin B12 injections are commonly used in these patients, but oral daily doses can also be effective if the high dose is maintained, and absorption is documented