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The Bottom Line Managing MTHFR mutations requires a personalized approach that combines lifestyle, dietary, and supplementation strategies

Three points define its use

doi:10.3945/an.117.015628

Most people get enough vitamin B12 in their diet, but some need supplementation

As a key coenzyme in mitochondrial energy metabolism, increased NAD enhances mitochondrial oxidative phosphorylation, promotes triglyceride breakdown in adipocytes, and converts fat into energy for the body, thereby reducing adipose tissue accumulation