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Critical role of metabotropic glutamate receptor 4 in bone marrow-derived dendritic cells in the Th17 cell differentiation and the melanogenesis of B16 cells

Damage to the mitochondrial electron transport chain increases ROS leakage, further amplifying oxidative stress ( Lipid peroxidation forms a feedback loop that exacerbates ferroptosis and ARDS progression

doi: 10.1289/ehp.11868

In terms of combining with ferroptosis-related targets, FSP1 inhibitors in combination with GPx4 inhibitors, for example, RSL3 in combination with NPD4928 and icFSP1 can synergistically induce ferroptosis, overcoming the compensatory resistance of the tumor cells

No significant differences were observed between the HF6 and the HF6+D groups