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"Nonetheless, our findings suggest that strengthening oversight and aligning incentives for timely reporting of results from clinical trials outlined in postmarketing requirements and commitments may be necessary to ensure postapproval evidence fulfills its intended role in promoting evidence-based clinical decision-making." JAMA

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Measurement of intestinal permeability using 51 CrEDTA has been utilised in rodent [51] and human studies [52,53,54], however does require the participant to be exposed to a small amount of radiation [55]