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Rats were housed under with ad libitum source of food and water throughout the experiment

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The interacting Polar residues, hydrophobic interactions, and binding affinities of either n-hexadecanoic acid or L-carnitine with SIRT1 Our docking data revealed that n-hexadecanoic acid and L-car upregulate SIRT1

However, it is important to emphasize that these results cannot be attributed to L-carnitine alone: the observed efficacy relies on a cream combining multiple actives (L-carnitine, licochalcone A, and decanediol) and on its use in conjunction with photodynamic therapy