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This switch affects nearby neurons where the surge of lactate creates a rapid metabolic response in the neurons, with incoming lactate acting as an energy substrate, and depolarizing them to increase overall network excitability (Figure 2)

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PMID 30940813

Epidermal fatty acid binding protein (E-FABP) expression in nave CD8+ T cells facilitates linoleic acid transport via mitochondria and its incorporation into cardiolipin, which induces lipid peroxidation and mitochondrial ROS production, leading to apoptosis and reduced TNF production [84]

[DOI] [PMC free article] [PubMed] [Google Scholar] 139.Wu, F