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Cavalcante, M

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In cytoplasm, rapid autophagy induction by spermidine administration is achieved through inhibition of the lysine acetyltransferase EP300 (E1A-binding protein p300), primarily resulting in autophagy-relevant cytosolic protein deacetylation 30

In general MetS continues to be a clustering of symptoms that seem to play a major role as CVD and T2D risk factors, raising the necessity of encouraging these patients to pursue lifestyle changes