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We were therefore interested if inhibition of the AKT target protein hexokinase 2 (HK2) which catalyzes the rate limiting step of glycolysis by using the HK2 inhibitor 2-Deoxyglucose (2DG) would mimic the effects of the AKT inhibitor MK2206 on the antioxidant defense and survival after IR

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Explorations in Cellular Stress, Inflammation, and Homeostatic Signaling Another area of interest involves cellular stress responses and their regulatory pathways