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It catalyzes the first step of glutathione synthesis, which consumes one molecule of ATP and combines glutamate and cysteine to form -glutamylcysteine (-Glu-Cys)

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However, genomic studies using post-mortem or disease-affected tissues present inherent challenges, potentially obscuring cell-specific DNA methylation patterns

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T cells kill cells that have become cancerous or infected

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Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance

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