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In murine models of cachexia, ketogenic feeding preserved lean mass and extended survival, an outcome attributed to reduced systemic IL-6 and TNF- as well as direct effects of ketone bodies (primarily -hydroxybutyrate) on muscle proteolysis 376,377,378

Education about the limitations of surgical diagnosis and the appropriateness of clinical diagnosis requires time and skill that many providers lack (Culley et al., 2017)

Stimulatory nanoparticles can reprogramme antigen-presenting cells and enhance T-cell activation, as demonstrated in the 4T1 model [142]