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7-12 Depending on the level of pain control required, these agents may be sufficient as the sole pharmacologic treatment or may be used adjunctively with opioids or other types of pain control

According to 2023 CPIC pharmacogenomic guidelines, CYP2C19 poor metabolizers accumulate escitalopram at plasma concentrations equivalent to supratherapeutic doses in normal metabolizers, requiring a 50% dose reduction or an alternative antidepressant

Both acetonic and ethanolic extracts exhibited high levels of phenolic, flavonoid, and flavonol compounds, particularly in female shoots and shrub leaves

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