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3.4 Research Applications TB-500 has been investigated in a wide range of laboratory models: 4

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doi:10.1016/j.addbeh.2015.07.027

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In the brain, many PLP-dependent enzymes are involved in the metabolism of crucial amino acid or amine neurotransmitters such as dopamine, GABA, glycine, glutamate, and 5-hydroxytryptamine