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People who have trouble swallowing can open the capsule and mix the powder inside with yogurt, water, or orange juice

10.1002/pri.1782 7 AltunkayaJ.CravenM.LambeS.BeckleyA.RosebrockL.DudleyR.et al

Isolated mitochondria from whole mouse brain show a decrease in complex I activity, though there appeared to be an agent-specific difference in the magnitude of this reduction, with ISO inducing the largest response (96, 101)