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Morphological changes in the brain of elderly people can be observed fundamentally at a microscopic level (number of neurons, dendritic and synaptic loss, and accumulation of disease-specific misfolded proteins in the central nervous system) and are readily apparent in the brain of individuals suffering from neurodegeneration (van Ham et al., 2009

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Pilot study on the effect of ramelteon on sleep disturbance after traumatic brain injury: preliminary evidence from a clinical trial

In glutathione metabolism, a highly interconnected set of TFs and glutathione metabolism genes with fewer metabolites, with either positive or negative correlations, signifying a dynamic balance of activation and repression mechanisms (Fig

High ammonia levels can alter the pH of the culture media, negatively affect cell metabolism, and impair protein glycosylation, leading to suboptimal cell growth and function