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1h), tracing with (1,2,3,4- 13 C 4 )KG revealed that carbon flux from KG, when present, is destined in part for the TCA cycle under these conditions (Extended Data Fig

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Additionally, partially substituting zinc with more biocompatible metals (such as magnesium or calcium) within the MOF structure can stabilize the framework and diminish toxic ion release ( in vitro and in vivo models, are crucial for achieving a balance between efficacy and safety

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