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33 , 62876295, doi:10.1093/nar/gki939 (2005)

Transcriptomic analyses have revealed that genes encoding MRS2/MGT transporters are frequently upregulated in response to stress, such as Mg deficiency or osmotic stress, thereby enhancing Mg uptake and correcting ionic imbalances

kojic acid is one such ingredient

In particular, the melatonin peak is associated with the nadir in body temperature, together with maximum tiredness, lowest alertness and performance (59) (Figure 6)