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Key small residues that form the enlarged subsite A L in hTauT (G57, G60, G62, S301) are completely conserved in hPAT1 (G59, G62, G64, S268), suggesting a shared mechanism for accommodating the taurine sulfonate group (Supplementary Fig

These are due to factors such as a shortage of GPs, nurses and other primary care staff

Aliquot only the lyophilized powder if longer storage is required, then reconstitute small aliquots one at a time

Compounding pharmacies assign their own beyond-use dates based on USP 797 guidelines, and those dates can range from 28 to 90 days when refrigerated, depending on the pharmacy and the specific formulation

the heteroaryl moiety may be unsubstituted or substituted by one or more groups selected from halogen, haloalkyl, hydroxy, alkoxy, carbonyl, alkylamido, nitro, amino, dialkylamino, carboxy, thio or thioalkyl