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Improving the selectivity of covalent inhibitors is critical and can be optimized through various means, including adjusting the reactivity and reversibility of the electrophile (warhead), 571,572 non-covalent scaffolds, dosage, etc

Fuzzy matching has been implemented using the agrepfunction in R withmax.distance=0.02,ignore.case=TRUE

mg/d= miligrams by day A recent literature review proposes a dose of approximately 84 mg of ALA, 14.8 mg of EPA, 35.6 mg of DHA, 2511.3 mg of linoleic acid (LA) and 6.8 mg of arachidonic acid (AA) per day, administered on a schedule of approximately 4.65 days, accumulating 104 days over six months Table 2 [160]

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