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In studies of neutralizing mAbs (Supplementary Table 1), viral titres and lung pathology after nasal challenge were reduced in rhesus macaques that were administered a mAb directed against a proteolytic cleavage site in the SARS-CoV S protein that is required for host-cell entry 134

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These changes are almost always temporary and reversible

Defective bacterial phagocytosis is associated with dysfunctional mitochondria in copd macrophages