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Neurologic disease induced in transgenic mice by cerebral overexpression of interleukin 6

Figure 3 Figure 4 2.1.4 Ferroptosis and necroinflammation Cellular ferroptosis triggers the innate immune system by releasing damage-associated molecules associated with inflammation

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Subsequently, western blot and qRT PCR analyses confirmed that ERO1 expression was significantly increased in Tsc1- or Tsc2-null MEFs compared to control cells, and its level was reversed by mTORC1 inhibition with rapamycin treatment (Fig

Flavonoids such as quercetin and naringenin have significant ROS scavenging abilities, which help protect neuronal cells from oxidative damage ( 4.3 Inhibition of inflammation Natural products often possess anti-inflammatory properties that complement their antioxidant effects