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This action reduces the flow of inflammatory signals to the brain via the vagus nerve and circulation

Because I think one thing that both clinicians and patients like to be guided by is, Okay, if Im not seeing at least some response by X time interval, then I should move on or tweak or modify. So is there a certain time of response that you find is typical

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Azizzadeh releases the platysma muscle and decreases nerve activity in the nerves that counteract the smile mechanism so that the mouth can once again turn upward, restoring the patients ability to smile