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Harrington JS, Ryter SW, Plataki M, Price DR, Choi AMK

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[8] [10] [11] [12] This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by the nonsense (stop) codon TGA

Current therapeutic approaches that inhibit this pathway can be broadly categorized into two groups: pathway-specific inhibitors and treatments based on natural or synthetic compounds