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[7] [9] Patients with a history of oxalate nephrolithiasis (kidney stones) or hyperoxaluria should avoid high-dose vitamin C administration, as ascorbic acid is metabolized to oxalate, which may precipitate stone formation or exacerbate renal impairment

High concentrations given intravenously may be diluted using parenteral infusion solutions

This discipline reduces variability and makes published results more reproducible a recurring theme in peer review of peptide studies and a small but important contributor to data quality