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These models are particularly relevant for studying myocardial reperfusion injury and coronary artery disease, as well as for exploring the pathophysiology of I/R injury in other organs such as the liver and kidney

An engineered subcutaneously implanted catheter pump to enhance delivery of topotecan into the brain was examined to evaluate its safety, efficacy, and biological effects in a patient with recurrent GBM, demonstrating a promising outcome

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