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The n-6 PUFA biosynthesis pathway and ferroptosis Cells can directly take up AA (C20:4n-6) from their environment, and linolenic acid (LA, C18:2n-6), a precursor of AA and an omega-6 essential fatty acid, is much more abundant in human blood, implying that cells may need to synthesize AA directly from LA (Fig

Wu WY, Wang ZX, Li TS, Ding XQ, Liu ZH, Yang J, et al

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It is in fact to This is why autoimmune gastritis B12 deficiency deserves more attention

Free Radic Biol Med 1995, 19 (2), 227250