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The drug reduces hepatic glucose production, enhances glucose uptake in the peripheral tissues and increases insulin sensitivity 115

The study utilized HA with different molecular weightslow molecular weight (LMW) and high molecular weight (HMW)due to their presumed distinct biological activities

Liao YH, Jones SA, Forbes B, Martin GP, Brown MB (2005) Hyaluronan: pharmaceutical characterization and drug delivery

It also promotes collagen III synthesis, which provides flexibility and plays a critical role in the early stages of tissue remodeling

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