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Briefly, a RT-PCR-nested amplification was performed, and purified PCR products were quantified using the PicoGreen assay (Invitrogen, Carlsbad, CA, USA), and quality analysed using the BioAnalyzer DNA 1000 LabChip (Agilent, Santa Clara, CA, USA) prior to sequencing

GCH1 expression can inhibit lipid peroxidation through two mechanisms: (1) GCH1 can generate BH 4 , which functions to diminish endogenous oxidative radicals

Body mass index in mid-life is associated with a first stroke in men: a prospective population study over 28 years

However, when these oxidants accumulate within red cells, hemoglobin and other proteins are oxidized, leading to loss of function and RBC death

Wamstad, M