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Modeling alpha-synuclein pathology in a human brain-chip to assess blood-brain barrier disruption

Mol Cell Proteomics 1:376386

Parameter sensitivity analysis for the ED 50 s and T 1/2 s of estimated fluxes We defined the individual model parameter sensitivity ( S ) as follows: where x is the parameter value and f ( x ) is the ED 50 or T 1/2 for estimated fluxes