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[DOI] [PMC free article] [PubMed] [Google Scholar] 130.Alderson N.L., Chachich M.E., Frizzell N., Canning P., Metz T.O., Januszewski A.S., Youssef N.N., Stitt A.W., Baynes J.W., Thorpe S.R

Although synthesized in the cytosol by the consecutive actions of -glutamate-cysteine ligase (GCL) and glutathione synthetase (GS), glutathione is also present in the ER, which contains a small but functionally significant fraction of the total cellular pool 9

Positive pressure forces contaminants back through the needle opening when you withdraw, compromising sterility across all subsequent doses