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Blood serum APAP concentrations measured in these patients ranged from 4 to 284 mg/L (median 52 mg/L), and correlated positively with APAP signals measured with the HRMS-based method (r 2 = 0.89, table S7)

Although astrocyte dysfunction and iron dysregulation are increasingly recognized in AD pathology, their direct causal link to disease progressionand particularly to hypothesized central mechanisms such as ferroptosisrequires further validation in human contexts

Nuclear factor erythroid 2-related factor 2 and -catenin coactivation in hepatocellular cancer: biological and therapeutic implications