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Some peptides have shown antioxidant or inflammation-regulating effects in laboratory research

smallpox vaccine is highly effective from the acute administration within seven days of likely exposure, among those that can safely take the vaccine and are assuredly within the 7 days, means that uninfected, or perhaps even the early-infected cell populations, can rapidly produce sufficient quantities of IL-12, IL-18, IFNy, and factors to stimulate NK cells, and Variola-specific CTL's to overcome the viral evasion proteins and stop the infection in this early phase

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Because bulk cytosolic readouts obscure compartmental signals, measurement should rely on ER-targeted genetically encoded H 2 O 2 probes (e.g., roGFP-Orp1 or HyPer-ER), which report local peroxidatic events without cytosolic averaging and allow discrimination of ER-confined redox dynamics from extra-ER sources (Rashdan and Pattillo 2020